Transapical aortic valve implantation: is it ready for prime time?

Transapical Aortic Valve Implantation

Results Balloon redilation of the transcatheter valve was performed in 18 patients (5%), and additional second valves were implanted in 13 (4%). At the end of the procedure, 186 patients (52%) had no paravalvular or transvalvular regurgitation. In the remaining 172 patients, paravalvular leakage was observed in 113 (32%), transvalvular leakage in 47 (13%), and both in 12 (3%). Leakage was trace...

vertical gastric plication: is it ready for prime-time?

Transapical approach for transcatheter aortic valve implantation.

With the advancement of device technology and procedural techniques, most transcatheter aortic valve implantation (TAVI) procedures have been performed with the transfemoral approach in recent years (1). However, alternative approaches such as transapical, trans-subclavian, direct aortic and others still play an important role in patients with poor vascular access. Transapical approach is the o...

FGF23: is it ready for prime time?

Since the identification of fibroblast growth factor 23 (FGF23) more than a decade ago, interest in this hormone has grown dramatically among both nephrologists and endocrinologists. FGF23, initially identified in patients with rare forms of hypophosphatemia, is also increased in patients with chronic kidney disease (CKD). A handful of studies have suggested that increased circulating concentra...

Ginger: is it ready for prime time?

On the basis of substantial preclinical data showing the preventive efficacy of ginger and its constituents in vitro and in animal models, as well as a phase I pilot trial indicating that ginger extract is well tolerated in humans, Citronberg and colleagues conducted a pilot trial of ginger extract (2 g/day for 28 days) on biomarkers of cell proliferation [human telomerase reverse transcriptase...